Powerful antioxidant source from the grape seeds and grape skin. Grape seed extract is a great source of proanthocyanidins, powerful antioxidants. Proanthocyanidins are useful in stabilizing the venous system and thus may be helpful for varicose veins. Research has shown grape seed extract to be anti-inflammatory and anti-cancer. This is a less expensive alternative to Pycnogenol or pine bark extract.