CholestePure Plus II

A unique blend of phytosterols, berberine and clinically studied bergamot extract to promote healthy lipid metabolism and overall cardiometabolic health* Phytosterols are structural homologs of cholesterol that occur naturally in many plant foods. Over 30 years of research and 40 clinical trials suggest that phytosterols provide significant support for healthy lipid profiles. Well-established benefits of phytosterols on lipid balance stem primarily from the competition with cholesterol for occupancy in micelles, particles that carry cholesterol across the intestinal epithelium into the systemic circulation. Through this mechanism, phytosterols promote the excretion of cholesterol in the form of bile acids. Research indicates that the pine-derived phytosterols offered in this formula are comparable to phytosterols from other sources. Bergamot is a citrus fruit containing two newly discovered derivatives of the flavonoids hesperidin and naringenin. These compounds are naturally conjugated to a moiety known as hydroxymethylglutarate (HMG). In the liver, this unique molecule binds and modulates an enzyme known as HMG CoA reductase, which plays a central role in lipid biosynthesis. These unique compounds also target enzymes, transcription factors, and genes involved in lipid metabolism. In a study involving 192 volunteers, bergamot juice maintained healthy cholesterol levels in the normal range over a 30-day period. In a separate study of 80 subjects, 150 mg of flavonoids from Bergavit 40 bergamot extract supported healthy lipid and glucose profiles over a 6-month period. Berberine supports cardiometabolic health through a variety of mechanisms, including support for glucose and lipid metabolism, antioxidant defenses, and cytokine production. In a randomized, placebo-controlled trial involving 116 subjects, berberine provided statistically significant support for glucose and lipid metabolism. It also helps maintain endothelial function by promoting healthy vascular cell adhesion molecule-1 (VCAM-1) expression and healthy iNOS activity.* Supports phytosterol intake and overall cardiovascular health* Promotes healthy cholesterol metabolism* Improved, soy-free formula Made with vegan ingredients

Suggested Use

Recommendations: As a dietary supplement, take 2 capsules, 1-2 times daily, with meals.

Dietary Considerations

Gluten Free Soy Free Non-GMO

Warnings

Gluten-free, Soy-free, Non-GMO & Hypoallergenic Warning: Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use. Keep out of the reach of children. Store in a cool, dry place.

Product info

Serving Size: 2 Vegetable Capsule Servings Per Container: 60 Disclaimer Amount Per Serving Phytosterols (from PhytoPin pine (Pinus pinaster) phytosterol complex) 500 mg Berberine HCl 400 mg Bergavit 40 bergamot (Citrus bergamia) extract (fruit) (standardized to contain 39% flavonoids) 160 mg Other ingredients: Vegetarian capsule (cellulose, water)