Our Pycnogenol French Maritime Pine Bark Extract is produced by a European phytopharmaceutical company and is manufactured under strict European quality control standards without the use of harsh solvents. Like all European herbal extracts, the extraction of Pycnogenol is regulated to the same high standards as Over-The-Counter drugs. It is meticulously extracted to provide the optimal level of 90% natural occuring Proanthocyanidins. Pycnogenol is a registered trademark of Horphag Research, Ltd. Use of this product is protected by one or more of U.S. patents #4,698,360/#5,720,956/#6,372,266 and other international patents.