1. Decrease methionine containing foods. Methionine is the building block for homocysteine. Foods such as red meat and chicken are high methionine foods and have been shown to increase homocysteine.
  2. Eat much of your diet from green-leafy vegetables as these foods contain large quantities of B-vitamins which help to lower homocysteine.


  1. Control caffeine and alcohol intake as this has been linked to elevated homocysteine.
  2. Certain medications may increase the production of homocysteine.
    1. Anti-epileptic medications
    2. Glucophage (metformin)
    3. Levodopa
    4. Methotrexate
    5. Niacin
    6. Fenofibrates


  1. High Potency Optimized Folate 5 mg by Life Extension – 1 capsule daily. 5-MTHF is a methylated form of folate that is considered one of the most important tools in the battle against high homocysteine.
  2. Zinc 20 mg – 1 Tablet Twice Daily. Zinc is a helper in the conversion of homocysteine back into methionine. Note: Check your multi-vitamin and aim for 40 mg of zinc daily including all supplements.
  3. CystePlus – 500 mg twice daily. NAC helps in the removal of excess homocysteine by enhancing its metabolism.
  4. Two-A-Day Multivitamin – Blend of B-vitamins and other nutrients needed to properly metabolize homocysteine.

For Stubborn Homocysteine:

  1. Add Trimethylglycine (TMG) to the above regimen. 2 capsules twice daily

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